Researchers engineer 'Cas9' animal models to study disease, inform drug discovery

Researchers engineer 'Cas9' animal models to study disease, inform drug discovery

(http://www.sciencedaily.com/releases/2014/09/140925132835.htm)

Date:

September 25, 2014

Source:

Broad Institute of MIT and Harvard

Summary:

A new mouse model to simplify application of the CRISPR-Cas9 system for in vivo genome editing experiments. The researchers successfully used the new 'Cas9 mouse' model to edit multiple genes in a variety of cell types, and to model lung adenocarcinoma, one of the most lethal human cancers.