

Getting Drugs Past the Blood-Brain Barrier
Getting Drugs Past the Blood-Brain Barrier To treat neurological disease, researchers develop techniques to bypass or trick the guardian...


Immune Checkpoint Found Lacking in Type 1 Diabetes
Immune Checkpoint Found Lacking in Type 1 Diabetes Boosting levels of a the immunosuppressive protein PD-L1 in blood stem cells halts...


A more personal view of human-gene regulation
A more personal view of human-gene regulation A long-planned effort to examine gene expression and gene regulation in all the major...


Uncovering Functions of Circular RNAs
Uncovering Functions of Circular RNAs Recent research has revealed many surprises about circular RNAs, from findings that they are...


Heart’s Backup Pacemaker Mechanisms Identified
Heart’s Backup Pacemaker Mechanisms Identified The sinoatrial node is home to multiple pacemakers that keep the heart beating if the main...


Massive RNAi Screens Probe for Genes Important to Cancer
Massive RNAi Screens Probe for Genes Important to Cancer Two freely available databases include data on hundreds of human cancer cell...


Researchers Uncover Previously Unknown Immune Cell Subtypes
Researchers Uncover Previously Unknown Immune Cell Subtypes Using single-cell RNA sequencing, scientists characterize new populations of...


Stem Cells Seek Out Tumors Based on Stiffness
Stem Cells Seek Out Tumors Based on Stiffness The technique, demonstrated in mice using engineered mesenchymal stem cells, has potential...


Transgenic Mouse Illuminates Melanoma Metastasis
Transgenic Mouse Illuminates Melanoma Metastasis Glowing cells mark the routes of tumor spread by way of newly formed lymph vessels. By...


Bone Marrow Isn’t the Only Source of Platelets
Bone Marrow Isn’t the Only Source of Platelets Scientists have estimated that about half of murine platelet production occurs in the...